For those of us who have been living under a rock, or so enjoying the blissful benefits of domestic lockdown that we haven’t cared to pay attention, there’s a lot of interest in vaccine development to this pesky COVID19 thing. COVID19 is the disease that humans develop as a result of contracting the SARS-CoV-2 virus. … Continue reading THERE’S TIMMUNITY AND THERE’S BIMMUNITY, AND THEY’RE DIFFERENT.
In a Simpler Time… Once upon a time, Gentle Reader, in a Faculty office Far Far Away, an newly-minted Lecturer (Assistant Professor in the American and many other systems) found in their mail the very first paper they had ever been asked to review for publication in a Scientific Journal. Opening the magical envelope, they … Continue reading THE CURSE OF “ADDITIONAL DATA”.
So, how is the sausage made? Every grant received by the study section head is assigned to three reviewers, Primary, Secondary and Tertiary. One or occasionally two of these may be an ad-hoc reviewer brought in specifically for that proposal. Usually, all three are regular (“Permanent”) members. These reviewers have self-certified that they don’t have … Continue reading REVIEWING FOR THE NIH – HOW IT (ACTUALLY) WORKS – PART 3
The company I work for is currently hiring for Ph.D and non-Ph.D. scientists, and I’ve been helping the lab heads with interviews. Interviewing is always interesting of course, particularly when one doesn’t have a direct interest in the outcome. However, I interviewed one person whose story definitely rubbed me up the wrong way. The person … Continue reading MERGERS, REDUNDANCIES, AND OUTSOURCING
The review process is an interesting one, and it has changed a lot in the time I was a part of it (2005 – 2019). Two major events helped shape the change. The first was an attempt by NIH to, I believe, make the process of applying for funding more straightforward and accessible, particularly to … Continue reading REVIEWING FOR THE NIH – HOW IT (ACTUALLY) WORKS – PART 2
The degree of Doctor of Philosophy, usually called “Ph.D”, but sometimes called “D.Phil.” in universities such as Oxford for example, is universally recognized as the key to the door labelled “This Way to be an Independent Scientist.” It is a scientific apprenticeship, and like any other such, requires the production of a piece of work … Continue reading WHAT IS A Ph.D. ANYWAY, AND HOW DOES ONE GET ONE?
Unless one is actually within the American biological / health research community, it’s hard to imagine the size of the research effort that the National Institutes of Health funds. There are twenty-one so-called “Research Institutes”, founded between 1948, when the initial core of research themes was developed, to 2010, with the development of NIMHD – … Continue reading REVIEWING FOR THE NIH – HOW IT (ACTUALLY) WORKS – PART 1
Of course, neither students nor experienced scientists actually ask this question, but quite often, it’s perfectly clear that they should do. Let’s consider these three (hypothetical) datasets. For argument’s sake, let’s assign them as the secretion of IL-6 in micrograms per mL from LPS-stimulated macrophages isolated from patients with: no known autoimmune disease (A), systemic … Continue reading WHY ON EARTH WOULD I LOOK AT MY DATA – IT’S SIGNIFICANT, RIGHT?
“The Grumpy Old Professor.. don’t say you weren’t warned..” is obviously a bit tongue-in cheek, and in some posts it’s going to be more than others. I have been a Full Professor in a major US university, and I now hold the same title in an Adjunct context. I am pretty old by most counts, … Continue reading An Introduction…
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